The focus of research in our laboratory is molecular and genetic analysis of fruit ripening and related signal transduction systems with an emphasis on nutrient quality. We are investigating the regulation of ripening and nutrient quality using tomato as a model system. Experimental approaches include 1) positional cloning of loci known via mutation to harbor genes necessary for normal fruit development and ripening, 2) isolation of candidate ripening regulatory genes based on expression pattern or relationship to ripening-related signal transduction systems (e.g. ethylene, light), and functional analysis in transgenic plants, and 3) development and utilization of tools for functional genomics with current targets of exploration including genome-wide expression profiling during ripening and as related to fruit quality and nutritional composition.
Our laboratory is part of the USDA Agricultural Research Service (USDA-ARS) and is physically located in the Boyce Thompson Institute for Plant Research.
I team-teach the introductory molecular techniques module Concepts and Techniques in Plant Molecular Biology (BIOPL 483.1/PLPA463.1) with Susan McCouch and Joss Rose.
Additional Field memberships: Plant Biology, Horticulture.